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Hee Eun Kang Selected Research

Orotic Acid

12/2021Changes in digoxin pharmacokinetics associated with hepatic P-glycoprotein upregulation in rats with non-alcoholic fatty liver disease.
3/2021Pharmacokinetic changes of clozapine and norclozapine in a rat model of non-alcoholic fatty liver disease induced by orotic acid.
3/2020The pharmacokinetics of mycophenolic acid in rats with orotic acid induced nonalcoholic fatty liver disease.
1/2019Effects of Orotic Acid-Induced Non-Alcoholic Fatty Liver on the Pharmacokinetics of Metoprolol and its Metabolites in Rats.

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Hee Eun Kang Research Topics

Disease

5Neoplasms (Cancer)
07/2021 - 01/2011
4Non-alcoholic Fatty Liver Disease
12/2021 - 01/2019
4Hyperlipidemias (Hyperlipidemia)
05/2019 - 06/2012
2Hepatocellular Carcinoma (Hepatoma)
10/2019 - 03/2019
2Colonic Neoplasms (Colon Cancer)
05/2017 - 01/2016
2Necrosis
01/2013 - 02/2009
1Irritable Bowel Syndrome (Syndrome, Irritable Bowel)
03/2022
1Constipation
03/2022
1Carcinogenesis
07/2021
1Colorectal Neoplasms (Colorectal Cancer)
07/2021
1Alcoholic Fatty Liver
01/2019
1Ameloblastoma
11/2017
1Odontogenic Tumors (Dental Tissue Neoplasm)
11/2017
1Polyps
01/2016
1Hearing Loss (Hearing Impairment)
01/2016
1Anemia
08/2015
1Parkinson Disease (Parkinson's Disease)
01/2015
1Diabetic Neuropathies (Diabetic Neuropathy)
07/2014
1Breast Neoplasms (Breast Cancer)
07/2014
1Peripheral Nervous System Diseases (PNS Diseases)
07/2014
1Macular Degeneration (Age-Related Maculopathy)
06/2014
1Bronchitis
11/2013
1Infections
11/2013
1Hypertension (High Blood Pressure)
09/2013
1Body Weight (Weight, Body)
01/2013
1Mitochondrial Diseases (Mitochondrial Disease)
10/2009
1Iron Overload
10/2009
1Massive Hepatic Necrosis
02/2009
1Liver Diseases (Liver Disease)
02/2009
1Hepatitis
02/2009

Drug/Important Bio-Agent (IBA)

5Pharmaceutical PreparationsIBA
03/2021 - 11/2013
4Orotic AcidIBA
12/2021 - 01/2019
4Poloxamer (Poloxamer 407)IBA
05/2019 - 06/2012
3Member 1 Subfamily B ATP Binding Cassette TransporterIBA
12/2021 - 07/2014
3Proteins (Proteins, Gene)FDA Link
03/2021 - 07/2014
3Multidrug Resistance-Associated Protein 2IBA
03/2020 - 09/2016
3EnzymesIBA
03/2020 - 02/2009
2NiclosamideFDA Link
07/2021 - 05/2017
2Metformin (Glucophage)FDA LinkGeneric
07/2021 - 10/2009
2Mycophenolic Acid (Cellcept)FDA LinkGeneric
03/2020 - 09/2016
2Organic Anion TransportersIBA
03/2019 - 07/2014
1Serotonin ReceptorsIBA
03/2022
1N- ((1- (3- (1,2,3- triazol- 1- yl)propyl)piperidin- 4- yl)methyl)- 4- amino- 5- chloro- 2- methoxybenzamideIBA
03/2022
1Serotonin (5 Hydroxytryptamine)IBA
03/2022
1Digoxin (Digitek)FDA LinkGeneric
12/2021
1norclozapineIBA
03/2021
1Cytochrome P-450 CYP1A1 (CYP1A1)IBA
03/2021
1Clozapine (Clozaril)FDA LinkGeneric
03/2021
1Immunosuppressive Agents (Immunosuppressants)IBA
03/2020
1matrigelIBA
10/2019
1Dexamethasone (Maxidex)FDA LinkGeneric
10/2019
1Adenosine Triphosphate (ATP)IBA
10/2019
1ATP-Binding Cassette Transporters (ABC Transporters)IBA
10/2019
1Member 11 Subfamily B ATP Binding Cassette TransporterIBA
10/2019
1LipidsIBA
05/2019
1O-desmethyl metoprololIBA
01/2019
1Metoprolol (Toprol-XL)FDA LinkGeneric
01/2019
1Mitogen-Activated Protein KinasesIBA
11/2017
1DNA (Deoxyribonucleic Acid)IBA
11/2017
1ParaffinIBA
11/2017
1Glycogen Synthase Kinase 3IBA
05/2017
1ATP-Binding Cassette Sub-Family B Member 4IBA
09/2016
1PolyaminesIBA
01/2016
1herbacetinIBA
01/2016
1Biological ProductsIBA
01/2016
1Ornithine Decarboxylase (Decarboxylase, Ornithine)IBA
01/2016
1Fluorouracil (Carac)FDA LinkGeneric
08/2015
1DA-9701IBA
01/2015
1DA-9801IBA
07/2014
1AnionsIBA
07/2014
1CationsIBA
07/2014
1Peptides (Polypeptides)IBA
07/2014
1macrolactin AIBA
06/2014
17-O-succinyl macrolactin AIBA
06/2014
1hederacoside CIBA
11/2013
1AG NPP709IBA
11/2013
1Hydrochlorothiazide (Esidrix)FDA LinkGeneric
09/2013
1LigandsIBA
01/2013
1ChlorzoxazoneFDA LinkGeneric
01/2013
1Cytochrome P-450 CYP2E1 (CYP2E1)IBA
01/2013
1Epoxide HydrolasesIBA
06/2012
1Carbamazepine (Tegretol)FDA LinkGeneric
06/2012
1Carotenoids (Carotene)IBA
01/2011
1AntioxidantsIBA
01/2011
1astaxanthine (astaxanthin)IBA
01/2011
1IronIBA
10/2009
1phenylhydrazine (phenylhydrazine hydrochloride)IBA
10/2009
1sauchinoneIBA
10/2009
1GalactosamineIBA
02/2009
1Therapeutic UsesIBA
02/2009
1Alanine Transaminase (SGPT)IBA
02/2009
1Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA
02/2009

Therapy/Procedure

7Oral Administration
12/2021 - 06/2012
3Drug Therapy (Chemotherapy)
12/2021 - 05/2019
2Therapeutics
01/2019 - 11/2017
1Intravenous Infusions
03/2021
1Liver Transplantation
03/2020
1Transplantation
03/2020
1Aftercare (After-Treatment)
01/2013